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202409-33-4

202409-33-4 structural image
Product Name: Etoricoxib
Formula: C18H15ClN2O2S
Synonyms: 5-Chloro-3-[4-(methylsulfonyl)phenyl]-2-(2-methyl-5-pyridinyl)pyridine;5-Chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine
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CHEMICAL AND PHYSICAL PROPERTIES

Physical Description Solid
Solubility 3.28e-03 g/L

SAFETY INFORMATION

Signal word Danger
Pictogram(s)

Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H302:Acute toxicity,oral
H310:Acute toxicity,dermal
Precautionary Statement Codes P262:Do not get in eyes, on skin, or on clothing.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

COMPUTED DESCRIPTORS

Molecular Weight 358.8 g/mol
XLogP3 3.3
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 3
Exact Mass 358.0542766 g/mol
Monoisotopic Mass 358.0542766 g/mol
Topological Polar Surface Area 68.3 Ų
Heavy Atom Count 24
Formal Charge 0
Complexity 514
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Etoricoxib is a member of the class of bipyridines that is 2,3'-bipyridine, which is substituted at the 3, 5, and 6' positions by 4-(methylsulfonyl)phenyl, chlorine, and methyl groups, respectively. It has a role as a cyclooxygenase 2 inhibitor. It is a sulfone, a member of bipyridines and an organochlorine compound. Etoricoxib is a nonsteroidal anti-inflammatory medication (NSAID) that belongs to the COX-2 inhibitor group of medicine. As compared to other conventional NSAIDs, Etoricoxib Tablet is the most effective medication. It reduces swelling and pain in illnesses including gout, ankylosing spondylitis, persistent low back pain, osteoarthritis, and rheumatoid arthritis. This medication is also advised for people with minor pain following dental surgery. The medicine works by preventing the production of particular chemical messengers that cause inflammation and redness. In addition, unlike other NSAIDs, this medicine doesn't seriously harm the stomach. As a result, this medication is frequently prescribed.

RELATED SUPPLIERS

Gonane Pharma

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SHOBHA LIFE SCIENCES PRIVATE LIMITED

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KARUNESH REMEDIES

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product:202409-33-4 Etoricoxib IP/BP/EP/USP Complies as per Monograph

Gennex Laboratories Limited

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Mana Pharma

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Metrochem API Private Limited

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Otto Chemie Pvt Ltd

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Alembic Pharmaceuticals Limited

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All suppliers(39)