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200815-49-2

200815-49-2 structural image
Product Name: Arformoterol tartrate
Formula: C19H24N2O4.C4H6O6
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COMPUTED DESCRIPTORS

Molecular Weight 494.5 g/mol
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 11
Exact Mass 494.19004516 g/mol
Monoisotopic Mass 494.19004516 g/mol
Topological Polar Surface Area 206 Ų
Heavy Atom Count 35
Formal Charge 0
Complexity 521
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Arformoterol Tartrate is the tartrate salt of arformoterol, the (R,R)-enantiomer of formoterol and a long-acting beta-2 adrenergic agonist with bronchodilator activity. Arformoterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle and lead to an inhibition of release of inflammatory mediators from mast cells. This may eventually lead to an improvement of airway function.

RELATED SUPPLIERS

Cipla Ltd

1Y
product:200815-49-2 Arformoterol Tartrate 98%

MELODY HEALTHCARE PVT LTD

1Y
product:200815-49-2 98%

Ralington Pharma

1Y
product:Arformoterol Tartrate 98%
All suppliers(3)