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19608-29-8

19608-29-8 structural image
Product Name: Clascoterone
Formula: C24H34O5
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COMPUTED DESCRIPTORS

Molecular Weight 402.5 g/mol
XLogP3 3.9
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 5
Exact Mass 402.24062418 g/mol
Monoisotopic Mass 402.24062418 g/mol
Topological Polar Surface Area 80.7 Ų
Heavy Atom Count 29
Formal Charge 0
Complexity 769
Isotope Atom Count 0
Defined Atom Stereocenter Count 6
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity. By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and inflammatory pathways. In August 2020, FDA approved clascoterone for the first-in-class topical treatment of acne (acne vulgaris) in male and female patients 12 years and older. Clascoterone is also being investigated as a novel treatment for androgenetic alopecia.

RELATED SUPPLIERS

Shakti Life Science

1Y
product:19608-29-8 98%

Symbiotec Pharma Lab Pvt Ltd

1Y
product:Clascoterone 98%
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