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1953-04-4

1953-04-4 structural image
Product Name: Galantamine Hydrobromide
Formula: C17H22BrNO3
Synonyms: Galantamine hydrobromide;Galanthamine hydrobromide
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CHEMICAL AND PHYSICAL PROPERTIES

Collision Cross Section 166.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

SAFETY INFORMATION

Signal word Danger
Pictogram(s)

Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405:Store locked up.
P501:Dispose of contents/container to..…

COMPUTED DESCRIPTORS

Molecular Weight 368.3 g/mol
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 1
Exact Mass 367.07831 g/mol
Monoisotopic Mass 367.07831 g/mol
Topological Polar Surface Area 41.9 Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 440
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors. This agent may improve neurocognitive function in mild and moderate Alzheimer' s disease and may reduce abstinence-induced cognitive symptoms that promote smoking relapse.

RELATED SUPPLIERS

Aurobindo Pharma Limited

1Y
product:1953-04-4 / 69353-21-5 Galanthamine Hydrobromide 98%

Hetero Drugs Limited

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product:1953-04-4 / 69353-21-5 98%

AUROBINDO PHARMA LIMITED

Beijing
product:Galanthamine Hydrobromide
All suppliers(3)