18162-48-6
Product Name:
tert-Butyldimethylsilyl chloride
Formula:
C6H15ClSi
Synonyms:
TBDMSCl;tert-Butyldimethylchlorosilane;tert-Butyldimethylsilyl chloride, tert-Butylchlorodimethylsilane, TBDMSCl;TBDMSCl solution;tert-Butyl(chloro)dimethylsilane
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | White hygroscopic solid; [Merck Index] White crystals with a pungent odor; [Alfa Aesar MSDS] |
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Kovats Retention Index | 729 |
Chemical Classes | Toxic Gases & Vapors -> Chlorosilanes |
SAFETY INFORMATION
Signal word | Danger |
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Pictogram(s) |
Flame Flammables GHS02 Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09 |
GHS Hazard Statements |
H225:Flammable liquids H304:Aspiration hazard H314:Skin corrosion/irritation H336:Specific target organ toxicity,single exposure; Narcotic effects H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
COMPUTED DESCRIPTORS
Molecular Weight | 150.72 g/mol |
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Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 0 |
Rotatable Bond Count | 1 |
Exact Mass | 150.0631547 g/mol |
Monoisotopic Mass | 150.0631547 g/mol |
Topological Polar Surface Area | 0 Ų |
Heavy Atom Count | 8 |
Formal Charge | 0 |
Complexity | 81 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
Description
Tert-butyldimethylsilyl chloride is a silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. It is a derivatisation agent used in gas chromatography/mass spectrometry applications. It has a role as a chromatographic reagent. Tert-butyldimethylsilyl chloride is generally used as a reagent for installing TBS-protecting groups. A similar reagent is tert-butyldimethylsilyl trifluoromethanesulfonate (TBS-OTf).
RELATED SUPPLIERS
Lanya Chem Industries Pvt Ltd
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product:tert-Butyldimethylsilyl chloride 18162-48-6 / 187979-91-5 98%
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product:tert-Butyldimethylsilyl Chloride 97% For Synthesis 18162-48-6 99%