1786-81-8
Product Name:
Propitocaine hydrochloride
Formula:
C13H21ClN2O
Synonyms:
N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride;Prilocaine hydrochloride
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Collision Cross Section | 154.2 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
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COMPUTED DESCRIPTORS
Molecular Weight | 256.77 g/mol |
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Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 5 |
Exact Mass | 256.1342410 g/mol |
Monoisotopic Mass | 256.1342410 g/mol |
Topological Polar Surface Area | 41.1 Ų |
Heavy Atom Count | 17 |
Formal Charge | 0 |
Complexity | 218 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 2 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Prilocaine Hydrochloride is the hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. Prilocaine hydrochloride binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. This leads to a stabilization of the neuronal membrane and inhibits depolarization and results in a reversible blockage of nerve impulse generation and propagation along nerve fibres and subsequent reversible loss of sensation.