CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Solubility | 4.79e+00 g/L |
Decomposition | When heated to decomposition material emits toxic fumes of /nitrogen oxides/, ammonia, and hydrogen chloride. |
Other Experimental Properties | MW: 390.82. Crystals from water + isopropanol, undergoes phase change at 142 °C; decomposes at 175 °C /Valganciclovir hydrochloride/ |
SAFETY INFORMATION
Signal word | Warning |
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Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 354.36 g/mol |
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XLogP3 | -1.5 |
Hydrogen Bond Donor Count | 4 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 9 |
Exact Mass | 354.16516782 g/mol |
Monoisotopic Mass | 354.16516782 g/mol |
Topological Polar Surface Area | 167 Ų |
Heavy Atom Count | 25 |
Formal Charge | 0 |
Complexity | 528 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Valganciclovir is the L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine. It has a role as a prodrug and an antiviral drug. It is a member of purines and a L-valyl ester. It is functionally related to a guanine and a ganciclovir.
RELATED SUPPLIERS
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