CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White to off-white crystalline powder |
|---|---|
| Melting Point | 187-188 °C |
COMPUTED DESCRIPTORS
| Molecular Weight | 812.0 g/mol |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 13 |
| Rotatable Bond Count | 11 |
| Exact Mass | 811.47314329 g/mol |
| Monoisotopic Mass | 811.47314329 g/mol |
| Topological Polar Surface Area | 172 Ų |
| Heavy Atom Count | 58 |
| Formal Charge | 0 |
| Complexity | 1440 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 13 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Telithromycin is a ketolide, a novel form of macrolide antibiotic that is recommended for treatment of community acquired pneumonia. Telithromycin was approved for use in the United States in 2004 and subsequently linked to several cases of severe drug induced liver injury.