164579-32-2
Product Name:
PantoprazoleSodiumSesquihydrate
Formula:
C16H18F2N3NaO5S
Synonyms:
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt hydrate;Pantozol hydrate;Protonix hydrate
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SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
COMPUTED DESCRIPTORS
| Molecular Weight | 864.8 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 23 |
| Rotatable Bond Count | 14 |
| Exact Mass | 864.14584948 g/mol |
| Monoisotopic Mass | 864.14584948 g/mol |
| Topological Polar Surface Area | 185 Ų |
| Heavy Atom Count | 57 |
| Formal Charge | 0 |
| Complexity | 490 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 7 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Pantoprazole Sodium is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.
RELATED SUPPLIERS
TAGOOR LABORATORIES PVT LTD
2Y
product:164579-32-2 Pantoprazole Sodium Sesquihydrate IP/Ph. Eur /USP/BP >98%