Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecas163451-81-8

163451-81-8

163451-81-8 structural image
Product Name: A77 1726
Formula: C12H9F3N2O2
Inquiry

CHEMICAL AND PHYSICAL PROPERTIES

Solubility Soluble in DMSO (practically insoluble in water).

SAFETY INFORMATION

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H225:Flammable liquids
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight 270.21 g/mol
XLogP3 3.3
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 2
Exact Mass 270.06161202 g/mol
Monoisotopic Mass 270.06161202 g/mol
Topological Polar Surface Area 73.1 Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 426
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Teriflunomide is an enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the anilino group of 4-(trifluoromethyl)aniline. Used for the treatment of relapsing forms of multiple sclerosis and rheumatoid arthritis. It has a role as an EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor, a tyrosine kinase inhibitor, a hepatotoxic agent, a drug metabolite and a non-steroidal anti-inflammatory drug. It is a nitrile, an enol, an aromatic amide, an enamide, a member of (trifluoromethyl)benzenes and a secondary carboxamide.

RELATED SUPPLIERS

KARPSCHEM LABORATORIES PVT. LTD.

1Y
product:163451-81-8 Leflunomide EP Impurity B Leflunomide USP RC B ; (Z)-2-cyano-3-hydroxy-N-(4- (trifluoromethyl) phenyl)but-2-enamide 96%

Glyra Health Care Pvt Ltd

product:163451-81-8 99%

SETV ASRV LLP

1Y
product:TERIFLUNOMIDE 163451-81-8 95-99 %
All suppliers(3)