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158930-09-7

158930-09-7 structural image
Product Name: Frovatriptan Succinate
Formula: C18H23N3O5
Synonyms: Frovatriptan succinate;Frovatriptan succinate monohydrate;R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate
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COMPUTED DESCRIPTORS

Molecular Weight 361.4 g/mol
Hydrogen Bond Donor Count 5
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 5
Exact Mass 361.16377084 g/mol
Monoisotopic Mass 361.16377084 g/mol
Topological Polar Surface Area 146 Ų
Heavy Atom Count 26
Formal Charge 0
Complexity 426
Isotope Atom Count 0
Defined Atom Stereocenter Count 1
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine. (NCI05)

RELATED SUPPLIERS

Hetero Drugs Limited

1Y
product:158930-09-7 Frovatriptan succinate 98%

Nosch Labs Pvt Ltd

1Y
product:158930-09-7 99%

Mylan Laboratories Ltd

1Y
product:Frovatriptan succinate 98%
All suppliers(3)