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156-57-0

156-57-0 structural image
Product Name: Cysteamine hydrochloride
Formula: C2H8ClNS
Synonyms: β-Mercapto-ethylamine hydrochloride;2-Amino-ethane-thiol hydrochloride;2-Aminoethanethiolhydrochloride, Cysteamine hydrochloride, 2-Mercaptoethylamine hydrochloride;2-Mercapto-ethyl-amine hydrochloride;Cysteaminium chloride
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CHEMICAL AND PHYSICAL PROPERTIES

Physical Description Solid; [Merck Index] White hygroscopic crystals; [Alfa Aesar MSDS]
Solubility >17 [ug/mL] (The mean of the results at pH 7.4)
Chemical Classes Biological Agents -> Amino Acids and Derivatives

SAFETY INFORMATION

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight 113.61 g/mol
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 1
Exact Mass 113.0065981 g/mol
Monoisotopic Mass 113.0065981 g/mol
Topological Polar Surface Area 27 Ų
Heavy Atom Count 5
Formal Charge 0
Complexity 10
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

A mercaptoethylamine compound that is endogenously derived from the COENZYME A degradative pathway. The fact that cysteamine is readily transported into LYSOSOMES where it reacts with CYSTINE to form cysteine-cysteamine disulfide and CYSTEINE has led to its use in CYSTINE DEPLETING AGENTS for the treatment of CYSTINOSIS.

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