CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid; [Merck Index] White powder; [Alfa Aesar MSDS] |
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Melting Point | 338 °C |
Solubility | 3600 mg/L (at 25 °C) |
LogP | -1.07 |
LogS | -1.48 |
Ionization Efficiency | Positive |
Caco2 Permeability | -5.37 |
Dissociation Constants | 9.45 |
Collision Cross Section | 118.5 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)] |
Chemical Classes | Biological Agents -> Nucleic Acids and Derivatives |
COMPUTED DESCRIPTORS
Molecular Weight | 112.09 g/mol |
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XLogP3 | -1.1 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 0 |
Exact Mass | 112.027277375 g/mol |
Monoisotopic Mass | 112.027277375 g/mol |
Topological Polar Surface Area | 58.2 Ų |
Heavy Atom Count | 8 |
Formal Charge | 0 |
Complexity | 161 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Uracil is a common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. It has a role as a prodrug, a human metabolite, a Daphnia magna metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite and an allergen. It is a pyrimidine nucleobase and a pyrimidone. It is a tautomer of a (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one.