143-71-5
Product Name:
HYDROCODONE BITARTRATE
Formula:
C22H27NO9
Synonyms:
4,5-Epoxy-3-methoxy-17-methyl-5α-morphinan-6-one (2R,3R)-2,3-dihydroxybutanedioate (1:1)
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COMPUTED DESCRIPTORS
Molecular Weight | 449.4 g/mol |
---|---|
Hydrogen Bond Donor Count | 4 |
Hydrogen Bond Acceptor Count | 10 |
Rotatable Bond Count | 4 |
Exact Mass | 449.16858144 g/mol |
Monoisotopic Mass | 449.16858144 g/mol |
Topological Polar Surface Area | 154 Ų |
Heavy Atom Count | 32 |
Formal Charge | 0 |
Complexity | 642 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 6 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 2 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Hydrocodone Bitartrate is the bitartrate salt form of hydrocodone, a semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6.