14198-59-5
Product Name:
EMETINE HCL
Formula:
C29H41ClN2O4
Synonyms:
6′,7′,10,11-Tetramethoxyemetan dihydrochloride;Emetine dihydrochloride
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COMPUTED DESCRIPTORS
| Molecular Weight | 517.1 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 7 |
| Exact Mass | 516.2754855 g/mol |
| Monoisotopic Mass | 516.2754855 g/mol |
| Topological Polar Surface Area | 52.2 Ų |
| Heavy Atom Count | 36 |
| Formal Charge | 0 |
| Complexity | 679 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Emetine Hydrochloride is the chloride salt of a white crystalline bitter alkaloid isolated from the root of the plant Psychotria Ipecacuanha (ipecac root) and other plants with antiemetic and anthelminthic properties. Emetine inhibits protein synthesis in eukaryotic (but not prokaryotic) cells by irreversibly blocking ribosome movement along the mRNA strand and inhibits DNA replication in the early S phase of the cell cycle. (NCI04)