Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

Homecas1374743-00-6

1374743-00-6

1374743-00-6 structural image
Product Name: trilaciclib
Formula: C24H30N8O
Inquiry

COMPUTED DESCRIPTORS

Molecular Weight 446.5 g/mol
XLogP3 2.6
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 3
Exact Mass 446.25425761 g/mol
Monoisotopic Mass 446.25425761 g/mol
Topological Polar Surface Area 91.2 Ų
Heavy Atom Count 33
Formal Charge 0
Complexity 707
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Trilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing chemotherapy for extensive stage small cell lung cancer. CDK4 and CDK6 inhibitors have been investigated since the mid 1990s for their use in tumorigenesis and chemotherapy. Trilaciclib was first described in the literature in 2016. Trilaciclib was granted FDA approval on 12 February 2021.

RELATED SUPPLIERS

ExSyn Corp

1Y
product:1374743-00-6 Trilaciclib 98%

Apicore Pharmaceuticals Pvt Ltd

1Y
product:1374743-00-6 98%
All suppliers(2)

RELATED PRODUCTS