13035-61-5
SAFETY INFORMATION
Signal word | Warning |
---|---|
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
COMPUTED DESCRIPTORS
Molecular Weight | 318.28 g/mol |
---|---|
XLogP3 | 0.7 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 9 |
Rotatable Bond Count | 9 |
Exact Mass | 318.09508215 g/mol |
Monoisotopic Mass | 318.09508215 g/mol |
Topological Polar Surface Area | 114 Ų |
Heavy Atom Count | 22 |
Formal Charge | 0 |
Complexity | 458 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 4 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
Description
β-D-Ribofuranose 1,2,3,5-tetraacetate is a key acetylated ribose derivative in carbohydrate chemistry, used for its stability and solubility in organic solvents. It acts as a vital intermediate in synthesizing nucleosides, nucleotides, and complex carbohydrates, aiding the exploration of glycosylation mechanisms and glycosidic bond stereochemistry. Crucial for studying enzymatic pathways in nucleic acid metabolism, it is also used in enzymatic assays to evaluate glycosyltransferase and glycosidase activities. The compound's acetylated form enables selective deprotection, making it invaluable for constructing nucleotide analogs and modified sugars for biochemical and structural studies. It furthers synthetic methodologies in carbohydrate chemistry, contributing to the efficient production of ribose-based molecules for molecular biology and biochemistry research.