CHEMICAL AND PHYSICAL PROPERTIES
| Collision Cross Section | 399.88 Ų [M+2H]2+ [CCS Type: DT, Method: stepped-field] |
|---|
COMPUTED DESCRIPTORS
| Molecular Weight | 1347.6 g/mol |
|---|---|
| XLogP3 | -2.3 |
| Hydrogen Bond Donor Count | 15 |
| Hydrogen Bond Acceptor Count | 17 |
| Rotatable Bond Count | 42 |
| Exact Mass | 1346.72814643 g/mol |
| Monoisotopic Mass | 1346.72814643 g/mol |
| Topological Polar Surface Area | 544 Ų |
| Heavy Atom Count | 95 |
| Formal Charge | 0 |
| Complexity | 2620 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 10 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Substance P is a neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission. It has a role as a neurotransmitter, a vasodilator agent and a neurokinin-1 receptor agonist. It is a conjugate base of a substance P(3+).