117399-94-7
Product Name:
Endothelin-1 (human, porcine)
Formula:
C109H159N25O32S5
Synonyms:
Endothelin 1;Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem;ET-1;ET-1, CSCSSLMDKECVYFCHLDIIW
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SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P284:Wear respiratory protection. |
COMPUTED DESCRIPTORS
| Molecular Weight | 2491.9 g/mol |
|---|---|
| XLogP3 | -3.7 |
| Hydrogen Bond Donor Count | 32 |
| Hydrogen Bond Acceptor Count | 40 |
| Rotatable Bond Count | 47 |
| Exact Mass | 2491.0220087 g/mol |
| Monoisotopic Mass | 2490.0186539 g/mol |
| Topological Polar Surface Area | 1040 Ų |
| Heavy Atom Count | 171 |
| Formal Charge | 0 |
| Complexity | 5300 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 23 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)