115956-13-3
![115956-13-3 structural image](https://img.chemicalbook.in/CAS/GIF/115956-13-3.gif)
Product Name:
Dolasetron mesylate
Formula:
C20H26N2O7S
Synonyms:
Anzemet hydrate;Dolasetron mesylate monohydrate;Dolasetron methanesulfonate;Dolasetron methanesulfonate hydrate
Inquiry
SAFETY INFORMATION
Signal word | Warning |
---|---|
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 438.5 g/mol |
---|---|
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 3 |
Exact Mass | 438.14607235 g/mol |
Monoisotopic Mass | 438.14607235 g/mol |
Topological Polar Surface Area | 126 Ų |
Heavy Atom Count | 30 |
Formal Charge | 0 |
Complexity | 627 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 2 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 3 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Dolasetron Mesylate is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, dolasetron mesylate competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. (NCI04)