115-39-9
Product Name:
Bromophenol Blue
Formula:
C19H10Br4O5S
Synonyms:
Bromophenol Blue;Bromophenol Blue (BPB);3′,3′′,5′,5′′-Tetrabromophenolsulfonephthalein;3′,3″,5′,5″-Tetrabromophenolsulfonphthalein;3,3′,5,5′-Tetrabromophenolsulfonphthalein, BPB
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Odorless solid; Color varies (tan, orange, light pink, purple, or red) [CHEMINFO] Slightly soluble in water; [MSDSonline] |
|---|---|
| Color/Form | Hexagonal prisms from acetic acid and acetone |
| Melting Point | Decomposes at 279 °C (An orange discoloration with formation of a green sublimate sets in at 210 °C) |
| Solubility | Soluble in acetic acid |
| Dissociation Constants | pKa = 4.0 |
| Chemical Classes | Dyes -> Indicator Dyes |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H226:Flammable liquids H319:Serious eye damage/eye irritation H340:Germ cell mutagenicity H360:Reproductive toxicity H372:Specific target organ toxicity, repeated exposure H373:Specific target organ toxicity, repeated exposure |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 670.0 g/mol |
|---|---|
| XLogP3 | 5.8 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 669.69415 g/mol |
| Monoisotopic Mass | 665.69824 g/mol |
| Topological Polar Surface Area | 92.2 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 662 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Bromophenol blue is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye. It has a role as a two-colour indicator, an acid-base indicator and a dye. It is a sultone, an arenesulfonate ester, a 2,1-benzoxathiole, a member of phenols and an organobromine compound.