COMPUTED DESCRIPTORS
Molecular Weight | 1427.5 g/mol |
---|---|
XLogP3 | -10.3 |
Hydrogen Bond Donor Count | 22 |
Hydrogen Bond Acceptor Count | 32 |
Rotatable Bond Count | 37 |
Exact Mass | 1426.57178218 g/mol |
Monoisotopic Mass | 1426.57178218 g/mol |
Topological Polar Surface Area | 745 Ų |
Heavy Atom Count | 98 |
Formal Charge | 0 |
Complexity | 2750 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 20 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Phleomycin D1 is a glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. It has a role as an antineoplastic agent, an antifungal agent, an antimicrobial agent, an antibacterial agent and a bacterial metabolite. It is a chelate-forming peptide, a member of guanidines, a disaccharide derivative, a bi-1,3-thiazole and a glycopeptide.