1088-11-5
Product Name:
Nordazepam
Formula:
C15H11ClN2O
Synonyms:
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one;Desmethyldiazepam;Nordiazepam
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Solubility | >40.6 [ug/mL] (The mean of the results at pH 7.4) |
|---|---|
| Collision Cross Section | 160.1 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
| Kovats Retention Index | 2490 2494 2510 2507 2504 2462 2500 2493 2493 2493 2522 2521 2489 2480 2517 2554 2510 2555 2496 2522 2520 2500.8 2483.7 2523 2552 2502 2462 2529 2514.4 2480 2480 |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 270.71 g/mol |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 270.0559907 g/mol |
| Monoisotopic Mass | 270.0559907 g/mol |
| Topological Polar Surface Area | 41.5 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 376 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Nordazepam is a 1,4-benzodiazepinone having phenyl and chloro substituents at positions 5 and 7 respectively; it has anticonvulsant, anxiolytic, muscle relaxant and sedative properties but is used primarily in the treatment of anxiety. It has a role as a GABA modulator, an anxiolytic drug, an anticonvulsant, a sedative and a human metabolite. It is a 1,4-benzodiazepinone and an organochlorine compound.