CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
---|---|
Boiling Point | 378 |
Melting Point | 288-290 |
Solubility | freely soluble in water |
LogP | 1.42 |
LogS | -3.2 |
Stability/Shelf Life | Stable under recommended storage conditions. /Pramipexole dihydrochloride/ |
Decomposition | Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx), Sulfur oxides, Hydrogen chloride gas. /Pramipexole dihydrochloride/ |
Dissociation Constants | 5.6, 9.5 |
Other Experimental Properties | White to off-white powder, mp 296-301 °C (decomposes). Specific optical rotation: -67.2 deg at 20 °C/D(c = 1 in methanol). Solubility: water >20%; methanol ~8 %; ethanol ~0.5%. Practically insoluble in dichloromethane. /Pramipexole dihydrochloride monohydrate/ |
COMPUTED DESCRIPTORS
Molecular Weight | 211.33 g/mol |
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XLogP3 | 1.9 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 3 |
Exact Mass | 211.11431873 g/mol |
Monoisotopic Mass | 211.11431873 g/mol |
Topological Polar Surface Area | 79.2 Ų |
Heavy Atom Count | 14 |
Formal Charge | 0 |
Complexity | 188 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Pramipexole is a member of the class of benzothiazoles that is 4,5,6,7-tetrahydro-1,3-benzothiazole in which the hydrogens at the 2 and 6-pro-S-positions are substituted by amino and propylamino groups, respectively. It has a role as an antiparkinson drug, a dopamine agonist, an antidyskinesia agent and a radical scavenger. It is a member of benzothiazoles and a diamine. It is a conjugate base of a pramipexole(2+).
RELATED SUPPLIERS
Vepan Pharmatech Pvt Ltd
1Y
product:(S)-2-amino-4,5,6,7 -tetrahydro-6- (propylamino) benzothiazole dihydrochloride monohydrate