1022150-57-7
Product Name:
SGX-523
Formula:
C18H13N7S
Synonyms:
6-(6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylthio)quinoline, SGX523;Met Kinase Inhibitor VI, SGX523 - CAS 1022150-57-7 - Calbiochem
Inquiry
COMPUTED DESCRIPTORS
Molecular Weight | 359.4 g/mol |
---|---|
XLogP3 | 2.4 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 3 |
Exact Mass | 359.09531462 g/mol |
Monoisotopic Mass | 359.09531462 g/mol |
Topological Polar Surface Area | 99.1 Ų |
Heavy Atom Count | 26 |
Formal Charge | 0 |
Complexity | 494 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
SGX-523 is a member of the class of triazolopyridazines that is 6-(1-methylpyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazine-3-thiol in which the thiol hydrogen is replaced by a quinolin-6-yl group. It has a role as a c-Met tyrosine kinase inhibitor and a nephrotoxic agent. It is a member of quinolines, a triazolopyridazine, a member of pyrazoles, a biaryl and an aryl sulfide.