Anti-Cancer Gefitinib Raw Gefitinib Powder Pharmaceutical Gefitinib
Price | USD10.00 | USD15.00 | USD20.00 |
Packge | 1kg | 1kg | 1kg |
- Min. Order:1kg
- Supply Ability:500kg/Month
- Time:2022-06-29
Product Details
- Product NameGefitinib
- CAS No.184475-35-2
- EINECS No.643-034-7
- MFC22H24ClFN4O3
- MW446.9
- Appearancepowderwhite to beige
- Melting point 119-1200C
- storage temp. room temp
- Boiling point 586.8±50.0 °C(Predicted)
- density 1.322±0.06 g/cm3(Predicted)
Basic Info.
Product Description
Product Name | Gefitinib |
Appearance | White Powder |
CAS No. | 184475-35-2 |
MF | C22H24ClFN4O3 |
Gefitinib is the first molecular targeted drug to be used in non-small cell lung cancer treatment. Epidermal growth factors (EGF) are a kind of polypeptide with a relative molecular mass of 6.45x103, and they can bind with epidermal growth factor receptors (EGFR) on target cell membrane surfaces to trigger biological effects. EGFR is a type of tyrosine kinase (TK) type receptor, so when bound with EGF, it will promote TK activation in the receptor. This will cause tyrosine residue in the receptor to autophosphorylate and send continuous dividing signals into the cell, causing cell proliferation and differentiation. EGFR is abundant in human tissue, and it is highly expressed in malign tumors.
Application & Function
1. It is used as an intermediate in a variety of drugs, such as the contraceptive rodenticide, as a solvent and a plastic softener.
2. Mainly used in the dehydrogenation intermediates, also used as a solvent and plastic softeners The of the intermediate of pesticide rodenticide has insecticidal and repellent effects.
3. It is mainly used in dehydrogenation to produce. Pharmaceutical industry used in the synthesis of intermediates, it is also an important intermediate of synthesis benzene that split In addition, it also can be used as a solvent and plastic softeners, its chloride has insecticidal effect.
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- Since:2022-03-18
- Address: Room 601, Unit 1, Building 1, 188 Xinhuali, North Xinhua Road, Xiangdu District, Xingtai city, Hebei