Degarelix

Product Specifications

Description:

Antagonists of GnRH have proven to be an effective therapy for hormonally regulated cancers, such as prostate and some types of breast. As analogs of GnRH, they bind competitively and reversibly to GnRH receptors in the pituitary gland, thereby blocking the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In men, the reduction of LH triggers the ablation of testosterone secretion from the testes, and these castration-like levels have been essential in the effective management of advanced prostate cancer. In comparison to GnRH agonists, antagonists do not suffer from a potential flare of the disease as a result of an initial stimulation of the hypothalamic-pituitary-gonadal axis prior to down-regulation of the GnRH receptor. Moreover, GnRH antagonists provide beneficial effects more rapidly postdosing and result in a more efficient suppression of gonadotropin levels. With this in mind, degarelix acetate has been launched as a third-generation GnRH antagonist for the treatment of prostate cancer, and it joins other third-generation agents, ganirelix and cetronelix, on the market.

Applications:

Degarelix, is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.

Side Effects:

The most common adverse events included injection site reactions (pain, erythema, swelling, or induration), hot flashes, increased weight, and increases in serum levels of transaminases and gamma-glutamyltransferase. In addition to being contraindicated in patients with a previous hypersensitivity to degarelix, it should not be administered to women who are or may become pregnant as fetal harm can occur. Since long-term androgen deprivation therapy prolongs the QT interval, physicians should consider whether the benefits of degarelix outweigh the potential risks in patients with congenital long QT syndrome, electrolyte abnormalities, or congestive heart failure or in patients taking antiarrhythmic medications.

Company Profile

Wuhan wingroup Pharmaceutical Co.,Ltd located in Wuhan, Hubei Province, is a company dedicated to R&D,production and sales of chemical reagents, pharmaceutical intermediates, plantextracts and chemical raw materials. The company has a long-term cooperationwith Wuhan Research Institute and other universities. It is a pharmaceuticalenterprise oriented by the global pharmaceutical market demand and integratingthe research and development, industrialization and market operation ofinnovative drugs. At present, the company has submitted 10 domestic patents andone PCT patent (International Patent); And obtained the authorization of 7invention patents. The company has strong technical strength, advanced equipment,strict quality management system and high-quality after-sales service.

Over the years, our products have been widely sold to many countries and regions that we have established stable relations of cooperation with the traders and end users all around the world and have become a solid bridge among the suppliers, traders and end users.

Our Advantages

1. Quality control: We take quality as our life. We strictly control the quality of each process and establish a complete quality control system. We promise to bring 100% best quality products to consumers.

2. Trade capacity: We focus on chemical, biological medicine international trade for more than 10 years. Has the abundant product and the trade ability. Cooperative customers all over the world, good reputation.

3. transport capacity: We have professional freight agents, customs clearance agencies set up in the destination. Deliver your package safely. According to the customer's transport needs can choose: FEDEX UPS TNT DHL  air charter and sea.

4. Carefully packing: 1kg, 5kg, 15kg, 20kg, 25kg can be packed in different specifications. Packaging can be customized according to customer requirements. Aluminum foil bag and carton. Ensure the safety of transportation. And free samples are available.

5. Quality service: We have a professional customer service team and after sales team. Being proficient in each language will guarantee your after-sale service.

Certificate

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Packing&Shipping

1.Inner double plastic bags----25kg/Fiber drum (35*35*45cm, GW: 28kg, NW: 25kg);

2.Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).

3.Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg,NW: 1kg).

1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post andother couriers, weight from 10g to 1000kg or even bulker.

2. Shipping details & shipping documents will be provided andsent by email.

3.We keep tracking the shippment until clients well received.

4.After years export shipping experience, with professional and experienced cooperated forwarders,we ensure that goods can be  delivered in multiple ways safetly and efficiently.

FAQ

Q1:Can I get some samples?

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2:Which kind of payment terms do you accept?

A: Payment by T/T, Western Union or Bitcoin.

Q3:Which transportation do we use?

A:Samples could be DHL, UPS, TNT, EMS, Fedex, and so on. For mass orders, it will be delivered by air or sea.

Q4:How about your delivery time?

Generally, it will take 3 to 5 days after receiving your advance payment.

Q5:How do you treat quality complaint?

A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q6:How can we trust you?

A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.

Q7:Do you test all your goods before delivery?

A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.