Factory high quality and low price ALAMETHICINRESEARCH GRADE
| Price | USD1.00 |
| Packge | 1g |
- Min. Order:1g
- Supply Ability:g/kg/Ton
- Time:2019-12-26
Product Details
- Product NameALAMETHICINRESEARCH GRADE
- CAS No.27061-78-5
- EINECS No.608-040-6
- MFC92H150N22O25
- MW1964.3078
- AppearanceDMSO solutionOff-white
- storage temp. -20°C
Heidi 0647
Email:heidi@coreychem.com
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ALAMETHICINRESEARCH GRADE Basic information
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Product Name:
Synonyms:
N-Acetyl-2-methylalanyl-L-prolyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-valyl-2-methylalanylglycyl-L-leucyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-α-glutamyl-N1;Alamethicin, Ready Made Solution;ALAMETHICINRESEARCH GRADE;alamethicin from trichoderma viride;Almethicin, Antibiotic U-22324, 6-(2-methylalanine)-8-L-leucine-9-de-L-valine-12-(2-methylalanine)-13a-endo-(2-methylalanine)-18-L-glutamine-19-(N(1)-(1-(hydroxymethyl)-3-methylbutyl)-L-glutamamide)-];Ac-2-MeAla-L-Pro-2-MeAla-L-Ala-2-MeAla-L-Ala-L-Glu(NH2)-2-MeAla-L-Val-2-MeAla-Gly-L-Leu-2-MeAla-L-Pro-L-Val-2-MeAla-2-MeAla-L-Glu-L-Glu(NH2)-phenylalaninol;(3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-AcetaMido-2-Methylpropanoyl)pyrrolidin-2-yl)-15-(3-aMino-3-oxopropyl)-30-isobutyl-21-isopropyl-3,3,6,9,9,2,18,18,24,24,33,33-dodecaMethyl-1,4,7,10,13,16,19,22,25,28,31-undecaoxo-2,5,8,11,1;Peptaibol coMplex. Additional synonyMs for the Major coMponent, alaMethicin I: AlaMethicin F30, AlaMethicin-gaMMa, U 22324
CAS:
MF:
C92H150N22O25
MW:
1964.3078
EINECS:
608-040-6
Product Categories:
Mol File:
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ALAMETHICINRESEARCH GRADE Chemical Properties
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Fp
87℃
storage temp.
2-8°C
form
DMSO solution
BRN
5213858
Stability:
Stable.
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Safety Information
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ALAMETHICINRESEARCH GRADE Usage And Synthesis
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Chemical Properties
solid
Uses
Alamethicin is an acidic linear peptaibol complex with potent antibiotic activity, containing 20 “amino acids”, with acetyl and phenylalaninol termini, produced by Trichoderma sp.. Alamethicin F30 acts an ionopohore, transporting ions through membranes and artificial lipid membranes and forming voltage-dependent ion channels in lipid bilayer membranes. Alamethicin is co-produced with a parallel, neutral, linear peptaibol complex (alamethicin F50). The relative composition of alamethicin is a variable mixture of the acidic and neutral complexes, but reports on alamethacin do not generally specify the ratio of F50 to F30, and comparative data between the complexes is scant.
Uses
Alamethicin is a monovalent cation ionophore which can mimic nerve action potential across artificial membranes. Alamethicin has also been used for studying membrane interactions of antimicrobial peptides.
Purification Methods
Recrystallise alamethicin from MeOH. [Panday et al. J Am Chem Soc 99 8469 1977.] The acetate has m 195-180o from MeOH/Et2O, and the acetate-methyl ester [64936-53-4] has m 145-140o from aqueous MeOH.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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