CK-636
| Price | USD5.00 |
| Packge | 5KG |
- Min. Order:1KG
- Supply Ability:1ton
- Time:2019-09-04
Product Details
- Product NameCK-636
- CAS No.442632-72-6
- EINECS No.200-256-5
- MFC16H16N2OS
- MW284.38
- Appearancepowderpeach to light tan
- storage temp. Keep in dark place,Sealed in dry,2-8°C
▼
▲
CK-636 Basic information
▼
▲
Product Name:
Synonyms:
CK-636;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;CK-0944636;CK-636 N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide;N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide CK636;CK-636, >=98%;CK-636(CK-0944636;442632-72-6
CAS:
MF:
C16H16N2OS
MW:
284.37604
EINECS:
Product Categories:
Mol File:
▼
▲
CK-636 Chemical Properties
▼
▲
storage temp.
2-8°C
solubility
DMSO: ≥20mg/mL
form
powder
color
peach to light tan
InChIKey
ACAKNPKRLPMONU-UHFFFAOYSA-N
CAS DataBase Reference
▼
▲
CK-636 Usage And Synthesis
▼
▲
CK-636 is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
CK-636 inhibits actin polymerization mediated by Arp2/3 complex in live cells, and reduces the formation of actin filament comet tails by Listeria in infected SKOV3 cells. CK-636 inhibits lamellipodia formation at the leading edges of migrating T cells, and causes reduced velocity. In addition, a substantial fraction of CK-636-treated T cells on zigzag patterns with an acute turning angle are trapped near the interfaces formed by the turning points of zigzag patterns.
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY