Benidipine hydrochloride
| Price | USD1.00 | USD2.00 |
| Packge | 1KG | 1KG |
- Min. Order:1KG
- Supply Ability:200kg
- Time:2019-09-02
Product Details
- Product NameBenidipine hydrochloride
- CAS No.91599-74-5
- EINECS No.663-500-3
- MFC28H31N3O6.HCl
- MW542.02
- Appearancepowderyellow
- Melting point 199-201°C
- storage temp. Inert atmosphere,Store in freezer, under -20°C
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Product Name:
Synonyms:
Conipros;rac-(4R*)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl 5-[(3R*)-1-benzylpiperidine-3-yl]·hydrochloride;(4R)-rel-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-methyl5-[(3R)-1-(phenylmethyl)-3-piperidinyl]esterhydrochloride;rac Benidipine Hydrochloride;Benidipine hydrochlo;3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl5-[(3R)-1-(phenylMethyl)-3-piperidinyl] ester, hydrochloride (1:1), (4R)-rel-;(4R)-rel-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester, hydrochloride (1:1);(4R)-rel-3,5-Pyridinedicarboxylic acid
CAS:
MF:
C28H31N3O6
MW:
505.56
EINECS:
663-500-3
Product Categories:
Mol File:
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Benidipine hydrochloride Chemical Properties
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Melting point
199-201°C
storage temp.
Desiccate at RT
solubility
DMSO: ≥20mg/mL
pka
7.34(at 25℃)
form
powder
color
yellow
InChIKey
DGVVISBYHUXFIU-UHFFFAOYSA-N
CAS DataBase Reference
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Safety Information
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Benidipine hydrochloride Usage And Synthesis
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Description
Benidipine hydrochloride is a new, long acting dihydropyridine calcium antagonist useful in the treatment of hypertension and angina pectoris. In experimental animals, benidipine hydrochloride dose dependently induced hypotension with a potency of 6 and 12 times more than nifedipine and nicardipine, respectively. It also exhibited a slow onset of action.
Chemical Properties
Yellow Crystalline Powder
Originator
Kyowa Hakko (Japan)
Uses
A dihydropyridine calcium channel blocker. Antihypertensive.
Brand name
Coniel
Biological Activity
Orally active antihypertensive agent which displays a wide range of activities in vitro and in vivo . Inhibits L-, N- and T-type Ca 2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
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Benidipine hydrochloride Preparation Products And Raw materials
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Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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