Seratrodast
| Price | USD7.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameSeratrodast
- CAS No. 112665-43-7
- EINECS No.692-169-8
- MFC22H26O4
- MW354.44
- AppearanceYellow-orange solid.Pale Orange to Yellow
- Melting point 118-120°C
- storage temp. Sealed in dry,Store in freezer, under -20°C
- Boiling point 522.3±49.0 °C(Predicted)
- density 1.140±0.06 g/cm3(Predicted)
JD607
| Product Name: | Seratrodast |
| Synonyms: | Seratrodast AA 2414;benzeneheptanoic acid, -(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-;(+-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7-phenylheptanoicacid;aa-2414;beta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-bezeneheptanoicaci;5-(2,4,5-trimethyl-3,6,-dioxo-1,4-cyclohexadien-1-yl)benzeneheptanoic acid;7-(3,5,6-trimethy1-1,4-benzoquinon-2-y1)-7-phenylheptanoic acid;7-phenyl-7-(2,4,5-trimethyl-3,6-dioxo-1-cyclohexa-1,4-dienyl)heptanoic acid |
| CAS: | 112665-43-7 |
| MF: | C22H26O4 |
| MW: | 354.44 |
| EINECS: | 692-169-8 |
| Product Categories: | ZAGAM;API;Heterocyclic Compounds;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 112665-43-7.mol |
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| Seratrodast Chemical Properties |
| Melting point | 118-120°C |
| storage temp. | Store at +4°C |
| Merck | 14,8459 |
| CAS DataBase Reference | 112665-43-7(CAS DataBase Reference) |
| Safety Information |
| RTECS | DA1600050 |
| Seratrodast Usage And Synthesis |
| Description | Seratrodast, a novel benzoquinone derivative, is the first thromboxane A2 (TxA2) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA2, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA2 mimic and by a variety of spasmogenic prostanoids including PGF2α, PGD2 and 9α,11β-PGF2. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer. |
| Chemical Properties | Pale Orange Solid |
| Originator | Takeda (Japan) |
| Uses | antibacterial |
| Uses | Thromboxane A2-receptor antagonist. Antiasthmatic |
| Brand name | Bronica |
| Biological Activity | Thromboxane A 2 (TP) receptor antagonist. Antiasthmatic agent; inhibits platelet aggregation and bronchoconstriction induced by a TXA 2 mimetic in guinea pigs. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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