603-50-9

Bisacodyl is Digestive system medication CAS:603-50-9

Bisacodyl is a contact laxative that can be administered orally or rectally. When it comes into contact with the mucosa of the large intestine or the submucosal plexus, the constipation stimulates the nerve endings, excites the parasympathetic nerves, and causes the normal reflex peristalsis to increase and lead to defecation. In addition, fecal stoppage can also act on the intestinal mucosa, reduce the absorption of water and ions, increase the accumulation of rectal water and ions, and soften the stool, thereby further improving the effect of laxative.
Functions:
1. Combination of bisacodyl with antiarrhythmic drugs such as amiodarone, benzyl bromide, disopyramide, quinidine can cause hypokalemia and induce torsades de pointes. Non-stimulating drugs should be used instead. laxative;
2. Combination with aspirin, bepridil, sutopride, terfenadine and vincamine can also increase the risk of hypokalemia;
3. Combination with digitalis drugs can not only induce hypokalemia but also induce the toxic effects of digitalis drugs.
4. Do not take milk or antacids within 1 hour before and after taking the medicine, to avoid the dissolving of the tablet coating too quickly and increase stomach and intestinal irritation.
5. When used together with H2 receptor antagonists cimetidine, ranitidine and famotidine, it may increase gastric and intestinal irritation.
6. When used with antihypertensive drugs and diuretics, care should be taken to avoid hypokalemia.

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