GAMBOGIC ACID
Price | USD1.00 |
Packge | 1kg |
- Min. Order:1g
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameGAMBOGIC ACID
- CAS No.2752-65-0
- MFC38H44O8
- MW628.75
- Appearancepowderyellow to orange
- storage temp. -20°C
- Melting point 88.5°C
- Boiling point 586.06°C (rough estimate)
- density 1.1057 (rough estimate)
GAMBOGIC ACID Basic information |
Product Name: | GAMBOGIC ACID |
Synonyms: | BETA-GUTTIFERIN;BETA-GUTTILACTONE;GAMBOGIC ACID;GUTTATIC ACID;GUTTIC ACID;(z)-methyl-3-pentenyl)-;1,5-methano-1h,3h,11h-furo(3,4-g)pyrano(3,2-b)xanthene-1-crotonicacid,3a,4,5,;3,3,11-tetramethyl-13-(3-methyl-2-butenyl)-11-(4-7-tetrahydro-8-hydroxy-alph |
CAS: | 2752-65-0 |
MF: | C38H44O8 |
MW: | 628.75 |
EINECS: | |
Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors |
Mol File: | 2752-65-0.mol |
GAMBOGIC ACID Chemical Properties |
Melting point | 88.5°C |
Boiling point | 586.06°C (rough estimate) |
alpha | D20 -685° (methanol) |
density | 1.1057 (rough estimate) |
refractive index | 1.5290 (estimate) |
storage temp. | Store at -20°C |
solubility | DMSO: ≥10mg/mL |
color | yellow to orange |
InChIKey | GEZHEQNLKAOMCA-XKZIYDEJSA-N |
Safety Information |
Hazard Codes | T |
Risk Statements | 25-36/37/38 |
Safety Statements | 26-45 |
RIDADR | UN 2811 6.1 / PGIII |
RTECS | PB9268200 |
GAMBOGIC ACID Usage And Synthesis |
Uses | antiinflammatory, cytotoxic, inhibits HeLa cells in vitro; |
Definition | ChEBI: A natural product found in Garcinia hanburyi. |
Biological Activity | Natural product isolated from the Garcinia hanburyi tree. Induces apoptosis in several tumor cell lines including T47D cells. Activates caspases with an EC 50 value of 0.78-1.64 μ M and competitively inhibits antiapoptotic Bcl-2 family proteins (IC 50 values are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μ M for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 respectively). Also blocks K IR 2.1 channels (EC 50 ≤ 100 nM). |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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