4'-N-benzoylstaurosporine
| Price | USD2.00 |
| Packge | 1kg |
- Min. Order:1kg
- Supply Ability:100kg
- Time:2019-07-06
Product Details
- Product Name4'-N-benzoylstaurosporine
- CAS No.120685-11-2
- EINECS No.999-999-2
- MFC35H30N4O4
- MW570.64
- AppearanceTan solidWhite
- storage temp. Sealed in dry,Store in freezer, under -20°C
- Melting point 235-260℃
- density 1.47±0.1 g/cm3(Predicted)
| 4'-N-benzoylstaurosporine Basic information |
| Product Name: | 4'-N-benzoylstaurosporine |
| Synonyms: | 4'-N-benzoylstaurosporine;Midostaurin, Benzoylstaurosporine, 4'-N-Benzoylstaurosporine, CGP 41251;Benzamide, N-((9S,10R,11R,13R)-2,3,9,10,11,12-hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-J)(1,7)benzodiazonin-11-yl)-N-methyl-;Benzamide, N-(2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-1-oxo-8,12-epoxy-1H,8H-2,7B,12A-triazadibenzo(A,G)cyclonona(cde)trinden-10-yl)-N-methyl-, (8alpha,9beta,10beta,12alpha)-;Benzoylstaurosporine;Cgp 41 251;Cgp 41251;Cgp-41251 |
| CAS: | 120685-11-2 |
| MF: | C35H30N4O4 |
| MW: | 570.646 |
| EINECS: | 999-999-2 |
| Product Categories: | antibiotic |
| Mol File: | 120685-11-2.mol |
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| 4'-N-benzoylstaurosporine Chemical Properties |
| Melting point | 235-260℃ |
| storage temp. | Store at 2-8 |
| solubility | Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml). |
| 4'-N-benzoylstaurosporine Usage And Synthesis |
| Uses | Midostaurin was shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit. |
| Definition | ChEBI: An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine. |
| Biological Activity | Broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms ( α , β , γ ), PDFR β , VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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