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Riboflavin-5-phosphate sodium
Riboflavin-5-phosphate sodium

Riboflavin-5-phosphate sodium

Price USD1.00
Packge 1kg
  • Min. Order:1g
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameRiboflavin-5-phosphate sodium
  • CAS No.130-40-5
  • EINECS No.204-988-6
  • MFC17H22N4NaO9P
  • MW480.35
  • InChIKeyOHSHFZJLPYLRIP-RLWRCNEPNA-M
  • AppearancepowderYellow to Dark Orange
  • storage temp. 2-8°C
  • Melting point >300°C
  • Water Solubility almost transparency
Riboflavin-5-phosphate sodium Basic information
Description References
Product Name: Riboflavin-5-phosphate sodium
Synonyms: riboflavin5’-(dihydrogenphosphate),monosodiumsalt;Riboflavin 5′-monophosphate sodium salt;flavin mononucleotide sodium*electrophoresis reag;riboflavin 5-(sodium hydrogen phosphate);SODIUM RIBOFLAVIN PHOSPHATE;RIBOFLAVIN 5-PHOSPHATE SODIUM USP;Riboflavine 5'-monophosphate Sodium salt, Ph Eur;FLAVIN MONONUCLEOTIDE SODIUM*ELECTROPHOR ESIS REAGEN
CAS: 130-40-5
MF: C17H20N4NaO9P
MW: 478.33
EINECS: 204-988-6
Product Categories: Biochemistry;Vitamins;Vitamins and derivatives;Vitamin Ingredients;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Vitamin series;TAZIDIME;vitamin;Inhibitors
Mol File: 130-40-5.mol
Riboflavin-5-phosphate sodium Structure
 
Riboflavin-5-phosphate sodium Chemical Properties
Melting point  >300°C
FEMA  2976
refractive index  41 ° (C=1.5, 5mol/L HCl)
storage temp.  2-8°C
solubility  H2O: soluble50mg/mL, clear, orange
Water Solubility  almost transparency
Merck  14,8201
Stability: Stable. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. Protect from light, air and moisture.
CAS DataBase Reference 130-40-5(CAS DataBase Reference)
EPA Substance Registry System Riboflavin 5'-(dihydrogen phosphate), monosodium salt(130-40-5)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  22-24/25-37/39-26
WGK Germany  3
F  3-8-10
MSDS Information
Provider Language
Riboflavin-5-phosphate sodium English
SigmaAldrich English
 
Riboflavin-5-phosphate sodium Usage And Synthesis
Description Riboflavin-5-phosphate sodium (sodium FMN) consist mainly monosodium salt of Riboflavin 5-phophate (FMN), the 5-monophosphate ester of riboflavin. Riboflavin-5-phosphate sodium is produced by direct reaction of riboflavin with a phosphorylating agent such as phosphorous oxychloride in an organic solvent.
Riboflavin 5-phophate (FMN) is essential as a coenzyme in various enzymic reactions in the body and is therefore used in the form of its salts, especially in the form of sodium FMN, as additive to drugs and human and animal food. Sodium FMN is also used as starting material for flavin adenine dinucleotide which is employed for treating vitamin B2 deficiency. It is used as a yellow food color additive (E106).  Riboflavin 5-phosphate sodium is fairly stable in air but is hygroscopic and sensitive to heat and light. The product may be stored for 33 months from the date of manufacture in the unopened original container and at a temperature below 15 °C.
References [1] https://en.wikipedia.org/wiki/Flavin_mononucleotide
[2] Scientific Opinion on the re-evaluation of riboflavin (E101(i)) and riboflavin-5’-phosphate sodium (E 101(ii)) as food additives, EFSA Journal 2013
[3] Patent US 5095115A: Preparation of riboflavin 5'-phosphate (fmn) and its sodium salt in a lactone
Chemical Properties solid
Uses One of the bioactive forms of Riboflavin. Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).
Uses antibacterial
Uses  
Purification Methods Purify FMN by paper chromatography using tert-butanol/water, cutting out the main spot and eluting it with water. It can also be purified by adsorption onto an apo-flavodoxin column, followed by elution and freeze drying. It crystallises from aqueous acidic solution. [Mayhew & Strating Eur J Biochem 59 539 1976, Beilstein 26 III/IV 2555.]

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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