Procarbazine hydrochloride
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product NameProcarbazine hydrochloride
- CAS No.366-70-1
- EINECS No.206-678-6
- MFC12H20ClN3O
- MW257.76
- Appearancepowderwhite to tan
- Melting point 223°C
- Water Solubility >=10 g/100 mL at 21.5 ºC
- storage temp. Inert atmosphere,2-8°C
- density 8.3 g/cm3
AD68
| Procarbazine hydrochloride Basic information |
| Product Name: | Procarbazine hydrochloride |
| Synonyms: | n-(1-methylethyl)-4-((2-methylhydrazino)methyl)benzamide hydrochloride;PROCARBAZINE HCL;PROCARBAZINE HYDROCHLORIDE;1-(p-isopropylcarbamoylbenzyl)-2-methylhydrazinehydrochloride;1-methyl-2-(p-isopropylcarbamoylbenzyl)hydrazinehydrochloride;1-methyl-2-p-(isopropylcarbamyol)benzohydrazinehydrochloride;2-(p-(isopropylcarbamoyl)benzyl)-1-methylhydrazinehydrochloride;chlorhydratede1-methyl2p(isopropylcarbamoyl)benzyl-hydrazine |
| CAS: | 366-70-1 |
| MF: | C12H20ClN3O |
| MW: | 257.76 |
| EINECS: | 206-678-6 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;API;Matulane |
| Mol File: | 366-70-1.mol |
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| Procarbazine hydrochloride Chemical Properties |
| Melting point | 223°C |
| storage temp. | -20°C Freezer |
| solubility | DMSO: ≥18mg/mL |
| color | white to tan |
| Water Solubility | >=10 g/100 mL at 21.5 ºC |
| Merck | 14,7758 |
| CAS DataBase Reference | 366-70-1(CAS DataBase Reference) |
| EPA Substance Registry System | Benzamide, N-(1-methylethyl)-4-[(2-methylhydrazino) methyl]-, monohydrochloride(366-70-1) |
| Safety Information |
| Hazard Codes | T |
| Risk Statements | 45-61-22-68 |
| Safety Statements | 53-36/37-45 |
| RTECS | XS4725000 |
| Toxicity | LD50 orally in rats: 785 ±34 mg/kg (Goldenthal) |
| Procarbazine hydrochloride Usage And Synthesis |
| Chemical Properties | Crystalline Solid |
| Uses | Antineoplastic;DNA replication inhibitor |
| Definition | ChEBI: A hydrochloride obtained by combining procarbazine with one equivalent of hydrochloric acid. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaki g of DNA strands. |
| General Description | White to pale yellow crystalline powder with a slight odor. Acid to litmus. |
| Air & Water Reactions | In the presence of moisture or in aqueous solution undergoes oxidation by atmospheric oxygen. Water soluble. |
| Reactivity Profile | Procarbazine hydrochloride is very sensitive to light. Stability is highest in aqueous acid and decreases with increasing pH. Degrades rapidly in alcoholic media and more slowly in aqueous media . |
| Fire Hazard | Flash point data for Procarbazine hydrochloride are not available; however, Procarbazine hydrochloride is probably combustible. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
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- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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