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Atazanavir
Atazanavir

Atazanavir

Price USD1.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:Customized
  • Time:2019-07-06

Product Details

  • Product NameAtazanavir
  • CAS No.198904-31-3
  • EINECS No.1308068-626-2
  • MFC38H52N6O7
  • MW704.86
  • Appearancepowderwhite to beige
  • Melting point 207-2090C
  • storage temp. -20°C
  • density 1.178±0.06 g/cm3(Predicted)

Product NO:SP1095

Atazanavir Basic information
Product Name: Atazanavir
Synonyms: ATAZANAVIR, BISULFATE SALT;Atazanavir;(3S,8S, 9S, 12S)-2,5,6,13-Pentaazatetradecanedioic Acid;3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-dimethyl Ester;Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate;(2S)-N-(3-{[(2S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoylamino][(4-(2-pyridyl)phenyl)methyl]amino}(1S,2S)-2-hydroxy-1-benzylpropyl)-2-(methoxycarbonylamino)-3,3-dimethylbutanamide;229975-97-7 (Sulfate 1:1);Aids057755
CAS: 198904-31-3
MF: C38H52N6O7
MW: 704.87
EINECS: 1308068-626-2
Product Categories: API;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;Inhibitor;peptides
Mol File: 198904-31-3.mol
Atazanavir Structure
 
Atazanavir Chemical Properties
Melting point  207-2090C
alpha  D -47° (c = 1 in ethanol)
storage temp.  -20°C Freezer
 
Safety Information
Hazardous Substances Data 198904-31-3(Hazardous Substances Data)
MSDS Information
 
 
Atazanavir Usage And Synthesis
Chemical Properties Crystalline Solid
Uses Atazanavir is a novel azapeptide protease inhibitor (PI)
Uses enzyme inhibitor
Uses Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral.
Definition ChEBI: A heavily substituted carbohydrazide that is an antiretroviral drug of the protease inhibitor (PI) class used to treat infection of human immunodeficiency virus (HIV).
Uses Atazanavir is an inhibitor of HIV-1 protease (EC50 = 2.6 nM). In isolated cells, it has additive to moderately synergistic antiviral effects when combined with other antiretroviral drugs. As a result, it is commonly used in vivo in combination therapy for HIV-1 infection. Atazanavir competitively inhibits UDP-gluronosyltransferase, which conjugates bilirubin for clearance, leading to hyperbilirubinemia in a significant portion of those receiving atazanavir therapy.

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

Recommended supplier

career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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