Thiabendazole
Price | USD1.00 |
Packge | 1KG |
- Min. Order:1G
- Supply Ability:100KG
- Time:2019-07-06
Product Details
- Product Name Thiabendazole
- CAS No.148-79-8
- EINECS No.205-725-8
- MFC10H7N3S
- MW201.25
- InChIKeyWJCNZQLZVWNLKY-UHFFFAOYSA-N
- Appearancepowderlight yellow
- storage temp. Sealed in dry,Room Temperature
- Melting point 298-301°C
- Water Solubility 0.005 g/100 mL
- density 1.2271 (rough estimate)
- Boiling point 446.0±37.0 °C(Predicted)
AD68
Thiabendazole Basic information |
Product Name: | Thiabendazole |
Synonyms: | STORITE;TBZ;TBZ(R);TECTO;TECTO(R);THIBENZOLE(R);THIABENDAZOLE (TM);THIABENDAZOL |
CAS: | 148-79-8 |
MF: | C10H7N3S |
MW: | 201.25 |
EINECS: | 205-725-8 |
Product Categories: | Xanthones;Heterocyclic Compounds;FUNGICIDE;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API's;API;COUMADIN;agrochemical |
Mol File: | 148-79-8.mol |
Thiabendazole Chemical Properties |
Melting point | 298-301°C |
density | 1.2271 (rough estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | 0-6°C |
solubility | Soluble in methanol and dimethyl sulfoxide. |
form | powder |
color | light yellow |
Water Solubility | 0.005 g/100 mL |
Merck | 14,9289 |
InChIKey | WJCNZQLZVWNLKY-UHFFFAOYSA-N |
CAS DataBase Reference | 148-79-8(CAS DataBase Reference) |
NIST Chemistry Reference | Thiabendazole(148-79-8) |
Safety Information |
Hazard Codes | N,Xi |
Risk Statements | 50/53-36/37/38 |
Safety Statements | 60-61-36-26 |
RIDADR | UN 3077 9/PG 3 |
WGK Germany | 2 |
RTECS | DE0700000 |
TSCA | Yes |
HazardClass | 9 |
PackingGroup | III |
HS Code | 29341000 |
Hazardous Substances Data | 148-79-8(Hazardous Substances Data) |
Toxicity | LD50 in mice, rats, rabbits (g/kg): 3.6, 3.1, >3.8 orally (Robinson) |
Thiabendazole Usage And Synthesis |
Description | Thiabendazole is a kind of fungicide and parasiticide. As a fungicide, it can be used for the treatment of mold, blight and many other fungal diseases occurring in fruits and vegetable. As an antiparasitic, it is capable of treating roundworms, hookworms, and other kinds of helminth species that can attack wild animals, livestock and humans. It also has effects of inhibiting the angiogenesis of cells. The mechanism of action is still not fully understood. It has found that Thiabendazole is capable of suppressing the helminth-specific mitochondrial enzyme fumarate reductase, further inhibiting the citric acid cycle, mitochondrial respiration and ATP production, leading to helminth’s death. It may also inhibit the microtubule polymerization processes. |
References | https://pubchem.ncbi.nlm.nih.gov/compound/thiabendazole#section=Top https://en.wikipedia.org/wiki/Tiabendazole |
Chemical Properties | Light yellow powder |
Uses | anticoagulant, rodenticide |
Uses | A drug used in the treatment of helminthiases |
Definition | ChEBI: A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium. |
General Description | White or cream-colored odorless, tasteless powder. Sublimes above 590°F. Fluoresces in acidic solution. Formulated as a dust, flowable powder or wettable powder for use as a systemic fungicide and anthelmintic. |
Air & Water Reactions | Insoluble in water. |
Reactivity Profile | Thiabendazole is incompatible with a number of pesticides, including copper-containing fungicides, and with highly alkaline materials. Thiabendazole is a chelating agent, binding many metals including iron, but not calcium |
Fire Hazard | Flash point data for Thiabendazole are not available; however, Thiabendazole is probably combustible. |
Agricultural Uses | Fungicide: Thiabendazole is a fungicide used to control blight, mold, stain and rot that are found on fruit and vegetables; Dutch elm disease; and diseases found in food storage and other diseases. It is also used to treat roundworms and similar conditions in livestock and humans. Registered for use in EU countries. A U.S. EPA restricted use Pesticide (RUP). U.S. Maximum Allowable Residue Levels for Thiabendazole and its metabolite benzimidazole (free and conjugated) in or on the following food commodities:[40CFR 180.242(a) (1)]: apple, wet pomace 12.0 ppm; Avocado (There are no U.S. registrations on the indicated commodity) 10.0 ppm; banana, post harvest 3.0 ppm; bean, dry, seed 0.1 ppm; beet, sugar, dried pulp 3.5 ppm; beet, sugar, roots 0.25 ppm; beet, sugar, tops 10.0 ppm; cantaloupe (There are no U.S. registrations on the indicated commodity) 15.0 ppm; carrot, roots, postharvest 10.0 ppm; citrus, oil 15.0 ppm; fruit, citrus, group 10, postharvest 10.0 ppm; fruit, pome, group 11, postharvest 5.0 ppm; mango 10.0 ppm; mushroom 40.0 ppm; papaya, postharvest 5.0 ppm; potato, postharvest 10.0 ppm; soybean 0.1 ppm; strawberry (There are no U.S. registrations on the indicated commodity) 5.0 ppm; sweet potato (postharvest to sweet potato intended only for use as seed) 0.05 ppm; wheat, grain 1.0 ppm; wheat, straw 1.0 ppm. [40CFR 180.242(a)(2)]: cattle, meat 0.1 ppm; cattle, meat byproducts 0.4 ppm; goat, meat byproducts 0.4 ppm; Hog, meat byproducts 0.3 ppm; horse, meat byproducts 0.4 ppm; milk 0.1 ppm; sheep, meat byproducts 0.4 ppm. [40CFR 180.2010]: Use/Limits: As a seed treatment for dry pea (including field pea, pigeon pea, chickpea or lentil), using a maximum application rate of 0.075 pounds of active ingredient per 100 pounds of seed. Vines or hay grown from treated seed may not be fed to livestock. |
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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