Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
China United Kingdom South Korea Germany Japan India
Inquriy
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomecompanyCapsaicin
Capsaicin
Capsaicin

Capsaicin

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameCapsaicin
  • CAS No.404-86-4
  • EINECS No.206-969-8
  • MFC18H27NO3
  • MW305.41
  • AppearanceOff-white solidOff-white
  • storage temp. 2-8°C
  • Water Solubility insoluble
  • Melting point 62-65 °C(lit.)
  • Boiling point 210-220 C
  • density 1.1037 (rough estimate)

AD68

 
Capsaicin Chemical Properties
Melting point  62-65 °C(lit.)
Boiling point  210-220 C
density  1.1037 (rough estimate)
refractive index  1.5100 (estimate)
FEMA  3404 | CAPSAICIN
Fp  113 °C
storage temp.  2-8°C
solubility  H2O: insoluble
Water Solubility  insoluble
Merck  14,1768
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 404-86-4(CAS DataBase Reference)
EPA Substance Registry System 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl-, (6E)-(404-86-4)
 
Safety Information
Hazard Codes  T,T+
Risk Statements  25-37/38-41-42/43-36/37/38
Safety Statements  22-26-28-36/39-45-36/37/39
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  RA8530000
F  10-21
HazardClass  6.1(a)
PackingGroup  II
Hazardous Substances Data 404-86-4(Hazardous Substances Data)
Capsaicin Usage And Synthesis
Application in Particular Diseases In Osteoarthritis:
  • Capsaicin, an extract of red peppers that causes release and ultimately depletion of substance P from nerve fibers, has been beneficial in providing pain relief in OA when applied topically over affected joints. It may be used alone or in combination with oral analgesics or NSAIDs.
  • To be effective, capsaicin must be used regularly, and it may take up to 2 weeks to work. It is well tolerated, but some patients experience temporary burning or stinging at the site of application. Patients should be warned not to get the cream in their eyes or mouth and to wash their hands after application.
  • Application of the cream, gel, or lotion is recommended four times daily, but tapering to twice-daily application may enhance long-term adherence with adequate pain relief.
Chemical Properties Off-White Crystalline Solid
Uses A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Uses K channel blocker; multiple sclerosis therapy
Uses analgesic (topical), depletes Substance P, neurotoxic
Uses Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Uses Capsaicin is used in many topical ointments used to relieve the pain of peripheral neuropathy (treatment of pain in the nerve endings near the surface of the skin).
Uses As a tool in neurobiological research.
Biological Activity Prototypic vanilloid receptor agonist (pEC 50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets. Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

Recommended supplier

career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY
HomePage About Us Contact us Terms Privacy Chemicalbook
Land Line: 040 - 40102781 Mobile contact: +91 9550333722