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Zidovudine
Zidovudine

Zidovudine

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NameZidovudine
  • CAS No.30516-87-1
  • EINECS No.623-849-4
  • MFC10H13N5O5
  • MW283.24
  • InChIKeyHBOMLICNUCNMMY-JUCUSOLINA-N
  • AppearancePowderWhite to Off-white
  • Melting point 113-115 °C (lit.)
  • Water Solubility 1-5 g/100 mL at 17 ºC
  • storage temp. 2-8°C
  • Boiling point 410.43°C (rough estimate)
  • density 1.3382 (rough estimate)

AD68

Zidovudine Basic information
Product Name: Zidovudine
Synonyms: 1-(4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;1-(4-azido-5-methylol-tetrahydrofuran-2-yl)-5-methyl-pyrimidine-2,4-quinone;1-[4-azido-5-(hydroxymethyl)-2-tetrahydrofuranyl]-5-methylpyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione;1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione;1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione;3'-Deoxy-3'-azidothymi
CAS: 30516-87-1
MF: C10H13N5O5
MW: 283.24
EINECS: 1308068-626-2
Product Categories: Amino Acids;Miscellaneous Natural Products;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;API's;Antiviral;HIV/AIDS/Related Products;API;VIOCIN
Mol File: 30516-87-1.mol
Zidovudine Structure
 
Zidovudine Chemical Properties
Melting point  113-115 °C(lit.)
alpha  D25 +99° (c = 0.5 in water)
Boiling point  410.43°C (rough estimate)
density  1.3382 (rough estimate)
refractive index  47 ° (C=1, H2O)
Fp  9℃
storage temp.  −20°C
solubility  H2O: 50 mg/mL
form  Powder
color  White to Off-white
Water Solubility  1-5 g/100 mL at 17 ºC
Sensitive  Light Sensitive & Hygroscopic
Merck  14,10123
InChIKey HBOMLICNUCNMMY-BWZBUEFSSA-N
CAS DataBase Reference 30516-87-1(CAS DataBase Reference)
EPA Substance Registry System Thymidine, 3'-azido-3'-deoxy- (30516-87-1)
 
Safety Information
Hazard Codes  Xn
Risk Statements  40-36/37/38-20/21/22
Safety Statements  36/37/39-45-36-26
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  XP2072000
10
Hazard Note  Harmful
HS Code  29349990
Hazardous Substances Data 30516-87-1(Hazardous Substances Data)
Toxicity LD50 in male, female mice, male, female rats (mg/kg): 3568, 3062, 3084, 3683 orally; >750 i.v. (all species) (Ayers)
Zidovudine Usage And Synthesis
Chemical Properties Off White Crystalline Powder
Uses antibacterial
Uses A potent and selective inhibitor of HIV-1 replication
Definition ChEBI: A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.
General Description Slightly off-white odorless powdery solid.
Air & Water Reactions Dust may form an explosive mixture in air. Water soluble. Hydrolysis occurs in strongly basic solutions .
Reactivity Profile Zidovudine is a azido compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.
Fire Hazard Flash point data for Zidovudine are not available; however, Zidovudine is probably combustible.
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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