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HomecompanyPosaconazole
Posaconazole
Posaconazole
Posaconazole

Posaconazole

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NamePosaconazole
  • CAS No.171228-49-2
  • EINECS No.682-747-8
  • MFC37H42F2N8O4
  • MW700.78
  • Appearancepowderwhite to beige
  • Melting point 170-1720C
  • storage temp. -20°C
  • Boiling point 850.7±75.0 °C(Predicted)
  • density 1.36±0.1 g/cm3(Predicted)

AD68

Tetracycline Basic information
Product Name: Tetracycline
Synonyms: 12,12a-pentahydroxy-6-methyl-1,11-dioxo-1;4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-Naphthacenecarboxamide;4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-4-(dimethylamino)-4;6-methyl-1,11-dioxy-2-naphthacenecarboxamide;abramycin;abricycline;achromycin(naphthacenederivative);achromycin(naphthracenederivatives)
CAS: 60-54-8
MF: C22H24N2O8
MW: 444.44
EINECS: 200-481-9
Product Categories: Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics T-ZAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Tetracyclines;Peptide Synthesis/Antibiotics;Inhibitors
Mol File: 60-54-8.mol
Tetracycline Structure
 
Tetracycline Chemical Properties
Melting point  175-177 °C(lit.)
alpha  D25 -257.9° (0.1N HCl); D25 -239° (methanol)
Boiling point  554.44°C (rough estimate)
density  1.3809 (rough estimate)
refractive index  1.6500 (estimate)
storage temp.  2-8°C
solubility  95% ethanol: soluble12.5mg/mL
pka pKa (50% aq DMF): 8.3, 10.2(at 25℃)
color  yellow to yellow orange
Water Solubility  Limited solubility in water. Soluble in 1M HCl with heating.
Merck  13,9271
CAS DataBase Reference 60-54-8(CAS DataBase Reference)
NIST Chemistry Reference Tetracycline(60-54-8)
EPA Substance Registry System 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5, 5a,6,11,12a-octahydro-3,6, 10,12,12a-pentahydroxy-6- methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-(60-54-8)
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  22-36-26
WGK Germany  3
RTECS  QI8750000
F  3-8-10
HS Code  29413000
Hazardous Substances Data 60-54-8(Hazardous Substances Data)
Toxicity LD50 in rats, mice (mg/kg): 807, 808 orally (Goldenthal)
Tetracycline Usage And Synthesis
Chemical Properties Crystalline Solid
Uses antibactierial
Uses antibacterial, antiamebic, antirickettsial
Uses Tetracycline is a linear, tetracyclic, broad spectrum antibiotic first prepared chemically by dechlorination of chlortetracycline and subsequently isolated from several Streptomyces species. Tetracycline has broad spectrum antibacterial and antiprotozoan activity, and acts by binding to the 30S and 50S ribosomal subunits blocking protein synthesis. Tetracycline is a pigment and, like many pigments, is degraded by light, oxygen, trace metal ions and pH variations. The purity of tetracycline is often variable, with significant levels of degradation products.
Uses Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis.
Uses Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 

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career henan chemical co

Henan China
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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