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Phenylephrine hydrochloride
Phenylephrine hydrochloride
Phenylephrine hydrochloride

Phenylephrine hydrochloride

Price USD1.00
Packge 1KG
  • Min. Order:1G
  • Supply Ability:100KG
  • Time:2019-07-06

Product Details

  • Product NamePhenylephrine hydrochloride
  • CAS No.61-76-7
  • EINECS No.200-517-3
  • MFC9H13NO2.ClH
  • MW203.67
  • InChIKeyOCYSGIYOVXAGKQ-OVMXBOEKNA-N
  • AppearanceCrystalline PowderWhite to almost white
  • Melting point 143-145 °C(lit.)
  • Water Solubility >=10 g/100 mL at 21 ºC
  • storage temp. 2-8°C

AD68

Phenylephrine hydrochloride Basic information
Product Name: Phenylephrine hydrochloride
Synonyms: (-)-3-[1(R)-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride;Phenylephrine Hydrochloride (200 mg);PHENYLEPHRINE HCL BP ((R)-3-HYDROXY-ALPHA-(METHYLAMINO) METHYL] BENZENEMETHANOLHYDROCHL ORIDE);)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride (R)-(−;Phenylephring Hydrochloride (R)-(−;(-)-alpha-hydroxy-beta-(methylamino)ethyl-alpha-(3-hydroxybenzene)hydrochlor;1-m-hydroxy-alpha-(methylaminomethyl)benzylalcoholhydrochloride;3-hydroxy-alpha-((methylamino)methyl)-,hydrochloride,(-)-benzenemethano
CAS: 61-76-7
MF: C9H14ClNO2
MW: 203.67
EINECS: 200-517-3
Product Categories: Adrenergic Agents;pharmaceutical raw material;Pharmaceutical intermediates;Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;API;AFRIN
Mol File: 61-76-7.mol
Phenylephrine hydrochloride Structure
 
Phenylephrine hydrochloride Chemical Properties
Melting point  143-145 °C(lit.)
alpha  -47 º (c=2, H2O)
refractive index  -45.5 ° (C=1, H2O)
Fp  9℃
storage temp.  Desiccate at RT
form  Crystalline Powder
pka pK1 8.77; pK2 9.84(at 25℃)
color  White to almost white
Water Solubility  >=10 g/100 mL at 21 ºC
Merck  14,7286
CAS DataBase Reference 61-76-7(CAS DataBase Reference)
EPA Substance Registry System Benzenemethanol, 3-hydroxy-.alpha.-[(methylamino) methyl]-, hydrochloride, (.alpha.R)-(61-76-7)
 
Safety Information
Hazard Codes  Xn,T,F
Risk Statements  22-36/37/38-39/23/24/25-23/24/25-11
Safety Statements  26-36-37/39-45-36/37-16-7
RIDADR  3249
WGK Germany  3
RTECS  DO7525000
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in rats (mg/kg): 17 ±1.1 i.p.; 33 ±2.0 s.c. (Warren, Werner)
Phenylephrine hydrochloride Usage And Synthesis
Chemical Properties white to almost white crystalline powder
Uses α-Adrenergic agonist. Mydriatic; decongestant.
Uses DECONGESTANTS
Definition ChEBI: A hydrochloride that is the monohydrochloride salt of phenylephrine.
General Description Odorless white microcrystalline powder. Bitter taste. pH (1% aqueous solution) about 5.
Air & Water Reactions May be sensitive to prolonged exposure to air and light. Water soluble.
Reactivity Profile Phenylephrine hydrochloride is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. Phenylephrine hydrochloride is also incompatible with butacaine, alkalis and ferric salts.
Fire Hazard Flash point data for Phenylephrine hydrochloride are not available; however, Phenylephrine hydrochloride is probably combustible.
Biological Activity α 1 -adrenoceptor agonist; pK i values are 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively.
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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