21187-98-4

Reduce blood sugar and improve coagulation function Gliclazide CAS:21187-98-4

Product name	Gliclazide
CAS	21187-98-4
Appearance	White powder
Melting point	165~172ºC
Assay	99.0%
Molecular Formula	C7H14N2.HCl

     Gliclazide is the second generation of sulfonylurea oral hypoglycemic drugs, which has the dual effects of lowering blood glucose and improving coagulation function. It can not only improve the metabolism of diabetic patients, but also improve or delay the occurrence of diabetic vascular complications. It is mainly used for mild and medium type II diabetes mellitus with no ketosis tendency and ineffective diet and exercise control after adult onset. It can also improve fundus lesions and metabolic and vascular dysfunction in diabetic patients. It can be combined with oral hypoglycemic drugs of biguidine and insu'lin in the treatment of insu'lin-dependent diabetes mellitus, which can reduce the dosage of insu'lin.
Application:
1. Hypoglycemic effect: this product is the second generation of oral sulfonylurea hypoglycemic drugs, and its effect is more than 10 times stronger than toluenbulurea. The mechanism of action is to stimulate pancreatic beta cells to release insu'lin, so that hyperglycemia dropped. This may be due to sulfonylureas binding to receptors on the surface of beta cells, increasing their activation and increasing the sensitivity of peripheral target tissues to insu'lin.
2. Reduce platelet aggregation and adhesion, and prevent fibrin deposition on microvessels.
3. Reduce cholesterol accumulation and plasma concentrations of arterial triphosphate triglycerides and fatty acids. The three functions, in addition to the treatment of metabolic disorders of diabetes, but also prevention and treatment of diabetes complications - vascular, retinal, renal lesions and the occurrence and development.
Packaging & Shipping

Company Information

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.
Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
FAQ
Q1. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q2. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.

Q3. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q4. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q5. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q6. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
 
Q7.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.