137-58-6

The local anesthetic Lidocaine CAS:137-58-6 Anesthetic Agents

 

Product Name:	Lidocaine
CAS:	137-58-6
MF:	C14H22N2O
MW:	234.34
EINECS:	205-302-8
Product Categories:	Halogenated Heterocycles;Pharma materials;Alphacaine, Xylocaine, lignocaine;REGITINE;Other APIs;API;Research Chemical
Mol File:	137-58-6.mol

Lidocaine works as a local anesthetic by reversibly closing sodium channels and blocking action potential transmission across nerve fibers. Sensory nerve fibers are blocked earlier than motor nerve fibers, so low doses of lidocaine can exert selective sensory block. Lidocaine also has antiarrhythmic effect, which belongs to class B antiarrhythmic drugs. It can reduce ventricular rate, shorten action potential time and absolute refractory period, and prolong relative refractory period. Lidocaine acts quickly and for a short time. Adding epine'phrine to lidocaine can reduce systemic absorption rate and thus prolong anesthesia time.
Application:
Lidocaine is a local anesthetic, also known as serocaine, which has replaced procaine in recent years and is widely used in local infiltration anesthesia in cosmetic surgery. Lidocaine blocks nerve excitation and conduction by inhibiting the sodium channel of nerve membrane. Its lipid solubility and protein binding rate are higher than that of procaine, and its ability to penetrate cells is stronger, its effect is faster, its action time is longer, and its action intensity is 4 times that of procaine. Clinical applications include infiltration anesthesia, epidural anesthesia, surface anesthesia (including mucosal anesthesia during thoracoscopy or abdominal surgery), and nerve conduction block. In order to prolong the time of anesthesia and reduce lidocaine poisoning and other side effects, epine'phrine can be added to anesthetics. Lidocaine may also be used to treat premature ventricular beats after acute myocardial infarction, ventricular tachycardia, digitalis poisoning, cardiac surgery, and ventricular arrhythmias caused by cardiac catheters, including premature ventricular beats, ventricular tachycardia, and ventricular fibrillation. Secondly, it is also used for epileptic persistent state with other anticonvulsant drugs ineffective and local or spinal anesthesia. But supraventricular arrhythmias are usually ineffective.
Packing & Shipping

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.
Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
FAQ
Q1. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q2. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.

Q3. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q4. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q5. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q6. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
 
Q7.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.