High Purity Sarms Raw Powder ACP105
| Price | USD9.90 | USD8.80 |
| Packge | 10g | 1000g |
- Min. Order:10g
- Supply Ability:1000kg/Month
- Time:2022-03-08
Product Details
- Product NameACP105
- CAS No.899821-23-9
- EINECS No.200-510-5
- MFC16H19ClN2O
- MW290.79
- AppearanceSolidOff-White to Pale Beige
- Melting point 160 °C
- Boiling point 479.8±45.0 °C(Predicted)
- density 1.28±0.1 g/cm3(Predicted)
- storage temp. Refrigerator
High Purity Sarms Raw Powder ACP105 CAS 899821-23-9
Basic Information
| Description | ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. |
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| Related Catalog | |
| Target | pEC50: 9.0 (AR wild type), 9.3 (AR T877A mutant). |
| In Vitro | ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. The half-lives of ACP-105 (compound 1) in human hepatocytes is measured and found to be 5.0 h. |
| In Vivo | ACP-105 enhances freezing in both sham-irradiated and irradiated mice (effect of ACP-105: F=5.44; p=0.028). For MAP-2 immunoreactivity in the cortex of sham-irradiated mice, there is a brain area×ACP-105 interaction (F=6.655; p=0.0027). While ACP-105 reduces MAP-2 immunoreactivity in the sensorymotor cortex, there is a trend towards increased MAP-2 immunoreactivity in the enthorhinal cortex. |
| Animal Admin | Mice Two-month-old C56Bl/6J female mice are kept on a 12:12 hr light-dark schedule (lights on at 6 AM) with lab chow and water given ad libitum. Following i.p. anesthesia (ketamine, 80 mg/kg and xylazine, 20 mg/kg), mice are sham-irradiated (n=7 sham vehicle-treated mice and n=7 ACP-105-treated mice) or irradiated (n=8 vehicle-treated mice and n=7 ACP-105-treated mice) using a dose of 10 Gy in a Mark 1 Cesium Irradiator. Twenty-four hours following irradiation, the mice are implanted with Alzet minipumps filled with ACP-105 at 1 mg/kg/day or 1.09 mg/200 μL in 10% Tween in saline or vehicle. Behavioral testing starts two weeks after irradiation. Mice receives three trials per day for three subsequent days. Mice are tested for fear conditioning in week 2. During contextual fear conditioning, mice learn to associate the environmental context with a mild foot shock. Contextual conditioned fear is assessed during the first 3 minutes of the contextual test trial when freezing behavior is most robust. Cued conditioned fear is assessed during the presentation of the tone (the last 3 minutes of the trial). |
| References |
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Our Company
Shanghai Biolang Biological Co., Ltd has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.
In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America, Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable prices and safe and effective transportation. Product can be ordered from milligrams to tons. Meet the purchase of new and old customers. We will not let you down.
Payment & Delivery
Why choose us?
1. Products with high purity and good quality
2. Choose the most suitable price according to customer needs to achieve a win-win situation.
3. Spot samples can be shipped quickly after payment, saving time for receiving goods.
4. Track the transportation of goods throughout the process
5. Safe raw materials from China
6. Have professional customs clearance capabilities and the best pre-sales and after-sales services.
our service
1. Cooperate with scientific research institutes and major factories to strictly control the entire process of products from raw materials to finished products
2. Customer first, we provide reasonable prices, high-quality products and timely delivery.
3. We can send the goods directly to your receiving address.
4. Quickly and accurately answer customers' doubts
5. If you place a large number of orders with us, we can provide preferential prices
6. Products can be packaged according to customer requirements.
FAQ
Q1: Can I get some samples?
Answer: Yes, we can provide free samples, but the freight is paid by our customers.
Q2: How to confirm the product quality before placing an order?
Answer: You can get samples of some products for free, you only need to pay the freight or arrange express delivery to us and get the samples. You can send us your product specifications and requirements, and we will manufacture products according to your requirements.
Q3: How to start an order or payment?
After the order is confirmed, the PI will be sent first with our bank information. Payment via T/T, Western Union, Letter of Credit, Alibaba Trade Assurance, Cashapp, Moneygram or Bitcoin.
Q4: How to place an order?
You can contact me through Trademanager, WhatsApp, Skype Online and other contact methods, tell me the product and quantity you need, and we will give you a quote. If you choose one of the above payment methods, we will arrange delivery for you.
Q5: Are there any discounts?
Answer: There are different discounts for different quantities.
Q6: How about your delivery time?
Answer: Generally speaking, it will take 3 to 5 days after receiving your prepayment. (Excluding Chinese holidays)
Q6: How do you deal with quality complaints?
Answer: First of all, our quality control will reduce quality problems to close to zero. If the quality problem is indeed caused by us, we will replace it for you free of charge or refund your loss.
Company Profile Introduction
Shanghai Biolang was established in 2004. Its headquarter and foreign trade department are located in Shanghai, its R&D center is located in Optics Valley Bio-City, its logistics center is located in Wuhan Biomedical Park, and its production bases are located in Luotian, Tongshan, Dongying, Pingxiang and other places. Beilang Bio's business involves the research and development of innovative drugs, the screening of compound crystal forms, the custom synthesis of pharmaceutical intermediates and APIs, and the import and export business, as well as the outsourcing procurement and agent sales of pharmaceutical chemicals. In order to better serve customers, Beilang Bio has assembled a R&D team composed of 5 Ph.Ds, which can carry out process development and pilot scale-up production of multiple projects at the same time. At the same time, it has established more than 5,000 square meters of cGMP production. The base has passed the FDA's ready-made review, which can realize the g-kg-t rapid response of pharmaceutical intermediates. Not only that, it has also built a 1,000-square-meter logistics center in Wuhan, a thoroughfare of nine provinces, and has a spot reserve worth more than 10 million. , It can realize the quick response to 1w orders in a single day. Beilang Biology has cooperated with many well-known universities and scientific research institutions such as Wuhan University, Shanghai University, China Medical University, China Pharmaceutical University, Shenyang Pharmaceutical University, Shanghai Institutes of Biological Sciences, China Institute of Biotechnology in the development of new drugs. Cooperation. At the same time, it has extensively cooperated with major pharmaceutical companies such as CSPC, Huayao Group, and Langbo Pharmaceutical to jointly develop export business. For a long time, colleagues regard Beilang as a long-term and reliable partner. We also hope to carry out more cooperation with colleagues in the industry, and work towards a better tomorrow.
- Since:2015-12-25
- Address: Room D621, Building 7, No. 228, Jingle Road, Langxia Town, Jinshan District, Shanghai