Zoledronic acid powder

Product name	Zoledronic acid
Other Name	ZOLEDRONATE;ZOLEDRONIC ACID;[1-hydroxy-2-(1h-imidazol-1-yl)-ethylidene]bisphosphonic acid;2-(Imidazol-1-yl)-1-hydroxyethane-1,1-diphosphonic Acid;CGP-4244;Zoledronic;Zoledronate acid;[1-HYDROXY-(1H-IMIDAZOL-1-YL)-PHOSPHONOETHYL] PHOSPHONIC ACI MONOHYDRATE
CAS	118072-93-8
Molecular formula	C5H10N2O7P2
Molecular Weight	272.09
Delivery time	Delivery within three days after payment
Delivery	Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity	99%
Package	Discreet and Hidden package according to specific requirement
Appearance	Whire Powder

1) Malignant hypercalcemia: hypercalcemia is a metabolic complication of malignant tumors. When serum calcium in the body is higher than 3.75mmol/L, hypercalcemia crisis may occur, which may eventually lead to death. Zoledronic acid can treat hypercalcemia by inhibiting bone resorption, reducing blood calcium levels, and increasing urinary calcium excretion. 14 patients with neoplastic hypercalcium were treated with zoledronic acid. The final results showed that zoledronic acid corrected blood calcium to 100% normal during the observation period, with a median effective response time of 5.07 days and a median maintenance time of 22.30 days. Studies have shown that 4mg zoledronic acid is recommended as the initial dose for hypercalcemia and 8mg zoledronic acid is recommended for relapsed or refractory hypercalcemia. 2) Bone metastasis: Zoledronic acid is a new generation of potent nitrogenous bisphosphonates, which has been clinically used in the treatment of multiple bone metastasis-related complications, including multiple myeloma, breast cancer, lung cancer, etc. Multiple myeloma (MM) is a malignant plasma cell disease in which tumor cells originate in the bone marrow from plasma cells, which are cells that develop to the final functional stage of lymphocyte development. Multiple myeloma therefore falls into the category of B-cell lymphoma. In previous clinical studies, bisphosphonates can relieve hypercalcemia in tumor patients, reduce the occurrence of pathological fractures, and relieve pain at the site of bone metastasis. Zoledronic acid is the third bisphosphonate, which has been proved to be the strongest anti-bone absorption drug. Ninety-four patients with myeloma were randomly divided into two groups: the control group was treated with standard chemotherapy alone, and the experimental group was treated with standard chemotherapy combined with zoledronic acid. The results indicated that the 5-year disease-free survival rate of the experimental group was higher. At present, zoledronic acid is mainly used as an adjunct drug for the treatment of complications such as bone metastasis, but with the development of clinical trials, studies have found that zoledronic acid has significant efficacy in the treatment of malignant tumors.
Packaging & Shipping

Company Information

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.
Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
FAQ
 Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.

Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.

Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
 
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.