150399-23-8

Name	Pemetrexed disodium
CAS NO	150399-23-8
Appearance	White crystalline powder
Identification	meet the requirement
Loss on drying	0.5%max
Residue on ignition	0.5%max
Havy metals	10ppm max
Assay	99%min

Pemetrexed disodium is the lilly developed a treatment for cancer drugs, patent protection to January 2017, pemetrexed disodium is a structure containing a core of pyrrole pyrimidine groups more targeted folate supplements, nucleotide synthase/dihydrofolate reductase dual inhibitors, by destroying the normal metabolism of intracellular folic acid dependent process, By inhibiting cell replication, tumor growth can be inhibited by simultaneously blocking three different enzyme targets that are critical for the survival of cancer cells. In February 2004, the us food and drug administration (FDA) approved and cisplatin combination treatment for a rare form of cancer, malignant pleural mesothelioma, malignant pleural mesothelioma is a rare pleural lung cancer, pemetrexed disodium can by blocking the unique mechanism of three kinds of key enzymes of cancer cell metabolism, so as to interfere with the cancer cell replication to further promote apoptosis of tumor cells. This regimen is a triple target with a synergistic inhibitory effect, which is superior to previous single-target regimens using cisplatin. At the same time, through the supplement of folic acid and vitamin can effectively control the toxic side effects, enhance the tolerance of patients.
Packaging & Shipping

Company Information

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.
Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
FAQ
 Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.

Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.

Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
 
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.