53179-13-8

Name	China Supplier Anti-Fibrosis Drug Pirfenidone for Health Treatment cas 53179-13-8
Appearance	White powder
Purity	99%
Port	Shanghai,tianjin,qingdao
Production capacity	20ton/month
Storage	Keep in a cool dry place
MOQ	10G

Introduction:

In vitro, pirfenidone can inhibit the proliferation of uterine leiomyoma cells and leiomyoma cells. Pirfenidone inhibits the formation of collagen in TGF-β-1-induced fibroblasts. Inhibition of , FGF and TGF-β-1 induced fibroblast proliferation. In the hamster model, pirfenidone, orally, prevents and treat bleomycin-induced pulmonary fibrosis. Pirfenidone can prevent chemically induced rat sclerosing peritonitis and can also be treated with keloid transplantation for nude mice.

Pirrenidone 0.01 1 mg / ml can inhibit the matrix and dose-dependent manner of serum stimulation of uterine fibroids and leiomyoma cell DNA synthesis, the compound without cytotoxicity, the collagen mRNA levels have no effect. Pirfenidone in the hamster pulmonary fibrosis model can reduce the level of collagen I mRNA levels before the disease, reduce lung proline levels and malondialdehyde and lung preservation of amino acid hydroxylase activity.

Application:

Pirfenidone is an antiinflammatory drug used to treat idiopathic pulmonary fibrosis. Anti-fibrosis agents, effective lung and pulmonary fibrosis models. Inhibit collagen production and fibroblast proliferation. Regulate the level of cytokines after oral administration of the body. Free radical scavengers and lipid peroxidation inhibitors. Pirfenidone inhibits collagen production and fibroblast proliferation. Antibacterial and antiinflammatory properties have been shown in various pulmonary fibrosis animal models and in clinical trials.

Packaging & Shipping

Company Information

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.
Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
FAQ
 Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.

Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.

Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
 
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.