76144-81-5
| Price | USD30.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:9000kg/per week
- Time:2022-05-20
Product Details
- Product NameMildronate
- CAS No.76144-81-5
- EINECS No.682-135-0
- MFC6H14N2O2
- MW146.19
- AppearanceSolidWhite to Off-White
- Melting point 85-900C
- storage temp. Refrigerator
| Item name | Mildronate |
| CAS No. | 76144-81-5 |
| Purity | 99% |
| Package | Aluminum Bag;Drums |
| Shippment | DHL, FedEx, TNT, UPS, Post |
| Payment Term | T/T, Western Union, L/C |
| Storage | Common storage 2-8ºC, long time storage -20ºC |
| Shelf life | 2 years |
1 mildronate can improve the energy metabolism of cardiomyocytes, inhibit carnitine-dependent fatty acid oxidation, enhance intracellular glucose metabolism, provide energy to tissues through anaerobic glycolysis, and improve the symptoms of myocardial ischemia and hypoxia. It can be used in combination with other drugs (such as vasodilators and diuretics) in the treatment of ischemic heart disease 2 M flexor hydrazine can promote blood redistribution in the heart and brain ischemia area, 3 drug for the treatment of various urgent chronic brain disorder by improving fat metabolism process, to improve people's ability to work, alleviate the psychological and physiological hypertension syndrome, athletes in training and competition in the process of taking the drug can improve the performance of 4 To eliminate functional impairment of the nervous system during withdrawal syndrome in patients with chronic alcoholism, the drug also ameliorates retinal vasculopathy caused by nutritional disorders Membrane protection: myocardial ischemia causes nervous response of cardiomyocytes, resulting in increased decomposition of fatty acids in mitochondria, accumulation of fatty acid metabolites in cells, destruction of cell membrane devices, and increase of intracellular Ca++ by 6 Energy optimization function: flexor m hydrazine can reduce the accumulation of long-chain acyl carnitine, which inhibits carnitine rely on fatty acid oxidation, make the anoxic myocardial energy metabolism from fatty acid oxidation into a better glucose oxidation, which has prompted glycolytic pathway of anaerobic oxidation, so this product has the anti hypoxia utility and heart protection activity 7 Effects on energy metabolism enzymes: Meldonium also prevents isoproterenol-induced enhancement of serum lactate dehydrogenase (myocardial specific isozyme) liver heteroactivity and prevents increased creatine phosphokinase activity8 Influence on carnitine excretion, other studies have suggested the flexor m hydrazine in the body in addition to competitive inhibition betaine butyric acid hydroxylase, blocking the biosynthesis of carnitine, also the impact of competitive carnitine in renal reabsorption of 9 to protect ischemic heart: in the region of the myocardial ischemia, the anterior descending blocked not only reduces the organization level of ATP ADP and creatine phosphate also increased tissue levels of AMP and lactate, and reduced the value of the energy charge potential. Experimental results showed that meldonium inhibited the β -oxidation of fatty acids and thus was beneficial to the energy metabolism of ischemic myocardium
| Quantity(Metric Tons) | 1 - 1 | 2 - 20 | >20 |
| Est. Time(days) | 10 | 25 | To be negotiated |
Company Information
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
Our Services
1.Any inquiry or message will be replied within 12 hours.
2.Professional manufacturer. Welcome to visit our website.
3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
4.Fast delivery.
5.After-sale services
FAQ
Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.
Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.
Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.
Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.
Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.
Company Profile Introduction
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ，that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
- Since:2021-03-01
- Address: Room 1810, Future Time Business Building, 121 Zhongshan West Road, Qiaoxi Dist.