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Candesartan
Candesartan
Candesartan
Candesartan
Candesartan

139481-59-7

Price USD15.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:9000kg/per week
  • Time:2022-05-20

Product Details

  • Product NameCandesartan
  • CAS No.139481-59-7
  • EINECS No.604-138-8
  • MFC24H20N6O3
  • MW440.45
  • AppearancesolidWhite
  • Melting point 183-185°C
  • storage temp. Inert atmosphere,Store in freezer, under -20°C
  • Water Solubility Soluble in ethyl acetate, methanol, water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).
  • Boiling point 754.8±70.0 °C(Predicted)
  • density 1.41±0.1 g/cm3(Predicted)
Product name Candesartan
CAS Number139481-59-7
Synonyms 1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-ethoxy-1H-benzo[d]iMidazole-7-carboxylicacid;2-ethoxy-3-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]-3h-benzoimidazole-4-carboxylicacid;3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]Methyl]-2-ethoxy-3H-benziMidazole-4-carboxylicAcid;CandesartanM1;2-ETHOXY1-2Chemicalbook(1H-TETRAZOL-5YL)1,1-BIPHENYL)-4-YL)-4-YL)METHYL)1H-BENZIMIDAZOLE-7-CARBOXYLICACID;CandesartanCilexetilEPIMpurityG;1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic;1H-Benzimidazole-7-carboxylicacid,2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
Molecular formulaC24H20N6O3
Molecular weight440.45
Purity 99%
Appearance White powder
EINECS number 604-138-8


Candesartan, the prodrug of Candesartan ester, is a new class of drugs acting on the renin-angiotensin system (RAS) rapidly developed after angiotensin converting enzyme inhibitors (ACEI). Because it can selectively block angiotensin ⅱ receptors in circulatory system and tissues, it has better antihypertensive effect and fewer adverse reactions, so it is a promising antihypertensive drug.
Candesartan is an angiotensin receptor (AT1) antagonist that antagonizes angiotensin vasoconstriction by binding to the vascular smooth muscle AT1 receptor, thereby reducing peripheral vascular resistance It was also suggested that candesartan could inhibit the secretion of aldosterone by adrenal gland and play a certain antihypertensive role. 2 The experiments in patients with hypertension showed that repeated administration of candesartan could increase the concentration of plasma renin-active angiotensin and angiotensin. This product 2-8mg, once a day, can reduce systolic blood pressure diastolic blood pressure, left ventricular myocardial weight and peripheral vascular resistance, but has no significant effect on cardiac output, ejection fraction, renal vascular resistance, renal blood flow, glomerular filtration rate; It has no effect on cerebral blood flow in essential hypertension patients with cerebrovascular disorders

Packaging & Shipping

Quantity(Metric Tons)1 - 12 - 20>20
Est. Time(days)1025To be negotiated


Fine Chemicals Hexyl Chloroformate, CAS: 6092-54-2Fine Chemicals Hexyl Chloroformate, CAS: 6092-54-2Fine Chemicals Hexyl Chloroformate, CAS: 6092-54-2

Company Information

   Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.

Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services
FAQ
 Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.

Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.

Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.

Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.

Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.

Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.

Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.

Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
 
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.





Company Profile Introduction

Hebei Lingding Biotechnology Co., Ltd. is a professional business company ，that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.

Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.

The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.

 

Recommended supplier

Hebei Lingding Biological Technology Co., Ltd

Hebei China
  • Since:2021-03-01
  • Address: Room 1810, Future Time Business Building, 121 Zhongshan West Road, Qiaoxi Dist.
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